Detalhe da pesquisa
1.
IFN-λ3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans.
Infect Immun
; 92(2): e0050423, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38193711
2.
Distinct molecular phenotypes involving several human diseases are induced by IFN-λ3 and IFN-λ4 in monocyte-derived macrophages.
Genes Immun
; 23(2): 73-84, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35115664
3.
Functional genetic variants of the IFN-λ3 (IL28B) gene and transcription factor interactions on its promoter.
Cytokine
; 142: 155491, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33725487
4.
SARS-CoV-2 infection in India bucks the trend: Trained innate immunity?
Am J Hum Biol
; 33(6): e23504, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32965717
5.
Understanding the devastating second wave of COVID-19 pandemic in India.
Am J Hum Biol
; 33(6): e23671, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469036
6.
Association of IL28B single nucleotide polymorphism rs8099917 with response to treatment in genotype 3 HCV-infected patients from India.
Trop Gastroenterol
; 35(2): 96-102, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25470871
7.
Gender-dependent multiple cross-phenotype association of interferon lambda genetic variants with peripheral blood profiles in healthy individuals.
Mol Genet Genomic Med
; 12(1): e2292, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37795763
8.
A Novel Inactive Isoform with a Restored Reading Frame Is Expressed from the Human Interferon Lambda 4 TT Allele at rs368234815.
J Interferon Cytokine Res
; 43(9): 370-378, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36880961
9.
Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-λ3 or IFN-λ4 show distinct phenotypes.
J Leukoc Biol
; 110(2): 357-374, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205487
10.
Impaired replication of hepatitis C virus containing mutations in a conserved NS5B retinoblastoma protein-binding motif.
J Virol
; 83(15): 7422-33, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19458004
11.
Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A.
Hepatology
; 50(1): 25-33, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19489073
12.
Mutations in SARS-CoV-2 viral RNA identified in Eastern India: Possible implications for the ongoing outbreak in India and impact on viral structure and host susceptibility.
J Biosci
; 452020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32515358
13.
The Genetic Association of IFN-λs with Human Inflammatory Disorders Remains a Conundrum.
J Interferon Cytokine Res
; 39(10): 594-598, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31161954
14.
Identifying causal variants at the interferon lambda locus in case-control studies: Utilizing non-synonymous variant rs117648444 to probe the role of IFN-λ4.
Gene
; 664: 168-180, 2018 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29705128
15.
Confounding by Single Nucleotide Polymorphism rs117648444 (P70S) Affects the Association of Interferon Lambda Locus Variants with Response to Interferon-α-Ribavirin Therapy in Patients with Chronic Genotype 3 Hepatitis C Virus Infection.
J Interferon Cytokine Res
; 37(8): 369-382, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28727946
16.
A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma.
Sci Rep
; 7(1): 10500, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874741
17.
Roles for Transcription Factors Sp1, NF-κB, IRF3, and IRF7 in Expression of the Human IFNL4 Gene.
Viral Immunol
; 29(1): 49-63, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684959
18.
Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactions.
J Interferon Cytokine Res
; 34(7): 479-97, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24555572
19.
A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB-mediated gene transcription.
PLoS One
; 8(10): e75495, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24116050
20.
A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase.
J Biol Chem
; 283(29): 20535-46, 2008 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18442978